Hexadecane-Induced Hyperkeratinization of Guinea Pig Skin

Karyotype of Hairless Guinea pig

Chromosomal patterns of experimental animals are useful tools for cytogenetics research and animal breeding. Chromosome investigations of the hairless guinea pig are rare, therefore, karyotype of hairless guinea pigs (twelve male and female) was studied using metaphase spreads of bone marrows and G banding techniques. The chromosomes diploid number was 2n= 64 and polymorphism of three type chro...

Evaluation of Protective Effects of Nano-formulated Silymarin Against UV Radiation on Guinea Pig Skin

  Background: As increased outdoor activities of people, they are more exposed to UV radiation, which causes harmful effects on skin. Silymarin has protective potentials against DNA damage and non-melanoma skin cancers, and also it has anti-oxidant, anti-inflammatory, and immune regulation characteristics. Nano formulation of plant material showed to be more effective than common ones.   Object...

Guinea-pig Skin in Tissue Culture

Small pieces of guinea-pig skin were exposed to a uniform field of microwaves at X-band (8,730 MHz). Measurements showed that 26%of the incident energy was reflected, 34% was absorbed, and the remaining 40% was transmitted. Absorbed energy was converted to heat, causing a rise in the temperature of the skin. After exposure to microwaves the skin was maintained in vitro on a nutrienmedium. Uptak...

Effect of Sodium Valproate on Ouabain-Induced Arrhythmia in Isolated Guinea-Pig Atria

Sodium valproate (SV), an antiepileptic drug has several mechanism of action. It inhibits voltage sensitive Na+ channels and reduces intracellular Na accumulation. These actions are similar to that of both phenytoin and carbamazepine. We have investigated the direct cardiac action of SV and its effects on ouabain-induced arrhythmia in isolated guinea-pig atria. The guinea-pig atrium was dissect...

Some observations on the feeding of the guinea pig